T Lymphocytes

O T cells play a major role in the cell-mediated immuneresponse. These cells are produced in the bone marrow but their final stage of development occurs in the thymus, hence the abbreviation "T." There are three recognized subclasses of T cells.

• Cytotoxic T cells (CD8+) promote target cell destruction by activating cellular ap-optosis or aggressively killing the target cell via the release of cytotoxic proteins.

• Helper T cells (CD4+) are the great communicators of the immune response. Once activated, they proliferate and secrete cytokines that regulate effector cell function. Some helper T cells secrete cytokines that recruit cytotoxic T cells, B cells, or APCs, while others secrete cytokines that turn off the immune response once an antigen has been destroyed.

• Regulatory T cells, or suppressor T cells, suppress the activation of an immune response. The activity of these cells in organ transplant is not well elucidated.

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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