Tertiary Syphilis Drug of Choice

Benzathine penicillin 2.4 million units administered intramuscularly once weekly for 3 weeks.

Alternatives

In nonpregnant patients with a penicillin allergy, alternative regimens include doxycycline 100 mg orally two times daily for 4 weeks or tetracycline 500 mg orally four times daily for 4 weeks.

Postivo syphilis scroervng «warn

Perorm treponemal specific tesl

1

PoMrve treponemai-speofic test

Negative troponcmal-spestic test

——i

stage cf iniect>on; obtain test tost rose*

stage cf iniect>on; obtain test

Sgns or symptoms o< f or soconda ry

No dinical signs or symptoms (talent sypMis)

Benzathine Pontc*n G. 2.4 million units IM (sin^o dose)*

S«gis o< symptoms cA tertary (late) syphilis. HW-posit ivo patient

Of OthOfVWSO

mmunooompfomtted

Early latent Late latent

S«gis o< symptoms cA tertary (late) syphilis. HW-posit ivo patient

Of OthOfVWSO

mmunooompfomtted

Benzathine peooHm G. 2.4 milkon units IM

tost rose*

Conader other causes

Benzathine peooHm G. 2.4 milkon units IM

BenzatNne peraofen G. 2.4 mribon units IM once weekly tor3weefcs (3 dosos)

puncturo

Sgns. symptoms.

CSF findings consistent with neurosyphAs

Your Heart and Nutrition

Your Heart and Nutrition

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