The anemia is usually normochromic and normocytic

• Approximately 50% of children present with platelet counts of less than 50 x 103/ mm3 (50 x 109/L).

• The WBC may be normal, decreased, or high. About 20% of patients have WBCs

of over 100 x 103/mm (100 x 10 /L), which places them at risk for leukostasis.

• Uric acid is increased in approximately 50% of patients secondary to rapid cellular turnover.

• Electrolytes: Potassium and phosphorus are often elevated. Calcium is usually low.

• Coagulation disorders: Elevated prothrombin time, partial thromboplastin time, D-dimers; hypofibrinogenemia

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