Treatment Desired Outcomes

® The treatment goals for osteomyelitis are to eradicate the infection and prevent recurrence. Cure rates of greater than 85% have been reportedfor acute hematogenous osteomyelitis^,23 In contrast, chronic osteomyelitis is associated with higher failure rates largely due to the presence of necrotic bone.1 These patients typically require surgical intervention to remove the necrotic bone and tissue, and if applicable, to replace infected hardware.4,24 Comorbidities such as vascular insufficiency can further contribute to the poor outcomes seen with chronic osteomyelitis. Due to the high failure rates, treatment in this patient population may require prolonged therapy with the primary goal of preventing amputation of infected areas.2, ,7,25

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