Upon completion of the chapter the reader will be able to

1. Explain the rationale for using hematopoietic stem cell transplant (HSCT) to treat cancer

2. Compare the different types of HSCTs, specifically (a) the types of donors (i.e., autologous and allogeneic), (b) the source of hematopoietic cells (i.e., umbilical cord, peripheral blood progenitor cells [PBPCs], and bone marrow), and (c) the type of preparative regimen (i.e., myeloablative and nonmyeloablative).

3. List the nonhematologic toxicity to high-dose chemotherapy used in myeloablative preparative regimens, specifically busulfan-induced seizures, hemorrhagic cystitis, GI toxicities, and sinusoidal obstruction syndrome.

4. Develop a plan for monitoring and managing engraftment of hematopoiesis.

5. Explain graft-versus-host disease (GVHD).

6. Recommend a prophylactic and treatment regimen for GVHD.

7. Choose an appropriate regimen to minimize the risk of infectious complications in HSCT patients.

8. Evaluate the long-term health care of HSCT survivors.

Your Heart and Nutrition

Your Heart and Nutrition

Prevention is better than a cure. Learn how to cherish your heart by taking the necessary means to keep it pumping healthily and steadily through your life.

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