Upon completion of the chapter the reader will be able to

1. Discuss the epidemiology and impact of surgical wound infections on patient outcomes and health care costs.

2. Name and differentiate the four different types of wound classifications.

3. Recognize at least three risk factors for postoperative surgical site infections (SSIs).

4. Identify likely pathogens associated with different surgical operations.

5. Compare and contrast antimicrobials used for surgical prophylaxis and identify potential advantages and disadvantages for each antibiotic.

6. Discuss the importance of ^-lactam allergy screening and how this could impact resistance and health care costs.

7. Identify nonantimicrobial methods that can reduce the risk of postoperative infection.

8. Discuss the possible impact of antimicrobial-impregnated bone cement and how this affects the use of antimicrobial prophylaxis in surgery.

9. Discuss the importance of timing, duration, and redosing in relation to antimicrobial prophylaxis in surgery.

10. Recommend appropriate prophylactic antimicrobial(s) given a surgical operation.

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