Upon completion of the chapter the reader will be able to

1. Explain the underlying causes of sickle cell disease (SCD) and their relationship to patient signs and symptoms.

2. Identify the typical characteristics of SCD as well as symptoms that indicate complicated disease

3. Identify the desired therapeutic outcomes for patients with SCD.

4. Recommend appropriate pharmacotherapy and nonpharmacotherapy interventions for patients with SCD.

5. Recognize when chronic maintenance therapy is indicated for a patient with SCD.

6. Describe the components of a monitoring plan to assess effectiveness and adverse effects of pharmacotherapy for SCD.

7. Educate patients about the disease state, appropriate therapy, and drug therapy required for effective treatment and prevention of complications.

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