Pruritus, or itching, is a common symptom. Generalized itching may be a symptom of a diffuse skin disorder* or a manifestation of chronic renal or hepatic disease. Intense pruritus may be associated with lymphoma or Hodgkin's disease, as well as with malignancies of the gastrointestinal tract. In older individuals, pruritus may also be caused by dry skin alone. Pruritus ani is localized itching of the anal skin. It has many causes, including fistulas, fissures, psoriasis, parasites, poor hygiene, and diabetes.

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