Clinical Manifestations Of Sjogrens Syndrome

Sjogren Swollen Salivary Glands

Most patients with Sjogren's syndrome develop symptoms related to decreased salivary gland and lacrimal gland function. Primary Sjogren's syndrome patients generally complain of dry eyes, often described as a sandy or gritty feeling under the eyelids. Other symptoms such as itching of the eyes, eye fatigue, and increased sensitivity to light can accompany the primary symptoms. Many of these symptoms are due to the destruction of corneal and bulbar conjunctival epithelium and come under the...

Diagnosis Of Sjogrens Syndrome With Salivary Gland Biopsy

Sjogren Disease Histology

Incisional biopsy of minor salivary glands was introduced as a clinical diagnostic procedure for Sjogren's syndrome in 1966. Many studies since that time have examined the value of this biopsy procedure (Marx, Hartman, and Rethman 1988). One study graded inflammation in labial salivary gland biopsy specimens from patients with various rheumatologic diseases and in postmortem specimens (Chisolm and Mason 1968). A grading scheme of lymphocytes and plasma cells per 4 mm2 was established and has...

Diagnostic Imaging of Salivary Gland Pathology

Normal Volume Parotid Gland

Introduction Imaging Modalities Computed Tomography (CT) CT Technique Advanced Computed Tomography Magnetic Resonance Imaging (MRI) MRI Technique Spin-Echo T1 Spin-Echo T2 Gradient Recalled Echo Imaging (GRE) Fluid Attenuation Inversion Recovery (FLAIR) Dynamic Contrast Enhanced Magnetic Resonance Imaging Other Magnetic Resonance Imaging Techniques Ultrasonography (US) US Technique Radionuclide Imaging (RNI) Positron Emission Tomography (PET) Positron Emission Tomography Computed Tomography...

Parotid Gland Tumour Mri Radiology

Scan Mono Lymph Nodes

Axial CT scan (a) and corresponding PET scan (b) at the level of the parotid gland. Note the asymmetric slightly higher uptake on the right corresponding to partially resected parotid gland on the left, confirmed by CT. into the substance of the gland. The parotid duct emanates from the superficial anterior part of the gland and is positioned along the superficial surface of the masseter muscle. Along the anterior aspect of the masseter muscle the duct turns medially, posterior to...

Hereditary and Congenital Conditions

Shingles Eye Swollen Shut

Aplasia of one or all of the major salivary glands is a rare condition that may present with severe xerostomia, rampant caries, candidiasis, pharyngitis, and laryngitis. In addition, dental chipping (Mandel 2006) and recurrent herpes labialis (Heath, McCleod, and Pearce 2006) have been described as presenting signs of salivary gland aplasia. The condition may occur as part of a recognized syndrome, associated with other congenital anomalies, or as an isolated phenomena. Aplasia of the lacrimal...

Tumors of Salivary Gland Lymph Nodes

Scan For Sjogren

Primary lymphoma of the salivary glands is rare. Eighty percent of lymphomas of the salivary glands are found in the parotid gland and 20 in the submandibular gland, with only case reports of sublingual and minor gland involvement (Eraso, Lorusso, and Palacios 2005) (Figure 11.10). Other authors have found a higher incidence of submandibular involvement (39 ) (Dunn, Kuo, and Shih et al. 2004). In 121 parotid tumors 8.3 were lymphomas (Shine, O'Leary, and Blake 2006), and in 51 submandibular...

Yamamoto Cranioacupuncture Paris

Sialadenitis Pathology

Axial PET scan corresponding to the case illustrated in Figure 2.76. The mass in the right parotid gland (arrow) is hypermetabolic. Also note two foci of intense uptake corresponding to inflammatory changes in the tonsils. Figure 2.78. Axial contrast enhanced CT scan through the parotid glands demonstrating a large mass of heterogenous density and enhancement partially exophytic from the gland. Metastatic squamous cell carcinoma from the scalp was diagnosed. Figure 2.78. Axial...

Clinical Manifestations Of Sarcoidosis

Sarcoid Submadnibular Gladn

Sarcoidosis occurs most commonly in American blacks and northern European Caucasians. It is eight times more common in American blacks than American Caucasians (Hellmann 1993). Women are affected slightly more frequently than men. Patients with sarcoidosis generally present with one of the following four problems respiratory symptoms such as dry cough, shortness of breath, and chest pain (40-50 ) constitutional symptoms such as fever, weight loss, and malaise (25 ) extrathoracic inflammation...

Diagnosis Of Sarcoidosis With Salivary Gland Biopsy

Natural Medicine For Sarcoidosis

As with Sjogren's syndrome diagnoses with salivary gland biopsies, early stage disease is perhaps more readily diagnosed with a parotid biopsy rather than a minor salivary gland biopsy. It has been pointed out that cases of sarcoidosis that do not clinically produce parotid enlargement nonetheless show involvement at the microscopic level (Marx 1995). In this review, the labial biopsy was positive in 38 of cases while 88 of parotid biopsies were positive for sarcoidosis. The lesions of...