Can posterior spinal instrumentation be utilized in the setting of an acute spinal infection without an increased rate of infectionrelated complications

Experimental and clinical evidence supports the concept that bone infections are better controlled with antibiotics and bone stabilization than with antibiotics alone in an unstable osseous environment. In this setting, advantages of posterior spinal instrumentation include:

1. Preservation of spinal alignment and restoration of spinal stability following radical debridement

2. Increased fusion rates

3. Ability to correct kyphotic deformities

4. Avoidance of graft collapse or dislodgement

5. Rapid patient mobilization and early rehabilitation without the need for an external orthosis

Use of titanium alloys is preferable to stainless steel due to increased bacterial adherence to stainless steel implants.

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