The connective tissue network of skeletal muscle has a dynamic role during muscle differentiation and normal muscle growth and it serves as a supportive structure in skeletal muscle and tendon [3,4,33,34]. Collagen forms the linkages between the muscle and its associated collagenous tissues such as tendon or fascia, and is also the fibrillar component of the cell-to-cell connections both between individual muscle cells and between the muscle cells and neighboring small blood vessels and nerves. It gives coherence and mechanical strength and also functions as an elastic, stress-tolerant system as well as distributing the forces of muscular contractions in both muscle and tendon. The tensile strength is based on intra- and intermolecular cross-links, and the orientation and density of the fibrils and fibers. In addition, collagen like the other ECM compounds conforms to the microenvironment around single muscle fibers and participates in the growth of cells and tissue regeneration after damage .
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Thank you for deciding to learn more about the disorder, Osteoarthritis. Inside these pages, you will learn what it is, who is most at risk for developing it, what causes it, and some treatment plans to help those that do have it feel better. While there is no definitive “cure” for Osteoarthritis, there are ways in which individuals can improve their quality of life and change the discomfort level to one that can be tolerated on a daily basis.