Physical inactivity and the burden of cardiovascular disease in type 2 diabetes

Patients with type 2 diabetes have a two- to four-fold increased mortality from cardiovascular disease [6]. The ultimate goal of all therapies in type 2 diabetes is to reduce this burden. In the Aerobic Center Longitudinal Study discussed above [7], the association between low cardiorespiratory fitness and physical inactivity and total mortality in 1263 men with type 2 diabetes was also studied. After adjustment for age, preexisting and family history of cardiovascular disease, fasting glucose and cholesterol concentrations, overweight and hypertension, type 2 diabetic men in the low fitness group had a risk for all-cause mortality of 2. i. The majority of deaths were attributable to cardiovascular disease [7].

Fitness and Exercise

Fitness and Exercise

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