Prevalence and risk factors

In most series lacunar infarcts are thought to account for about one-quarter of all ischemic strokes, a proportion similar to cardioembolic stroke and infarcts due to large-vessel atherosclerosis. Patients with lacunar infarcts are on average a few years younger than patients with ischemic stroke in general. This is likely to be indirectly linked to the fact that cardioembolic sources become more prevalent with age and consequently patients with cardiac embolism tend to be older.

Lacunar infarcts are formed on a risk-factor profile that comprises age, gender, hypertension, diabetes, smoking, previous TIA and possibly ischemic heart disease. In particular, hypertension was initially thought to be a prerequisite for the development of small-vessel occlusion. However, later studies have demonstrated that the vascular risk-factor profile is not specific for lacunar infarction, but is largely similar to other stroke types [30]. Lacunar infarcts are also part of the clinical spectrum of cerebral autosomal dominant arteriopathy with subcortical infarcts and leuken-cephalopathy (CADASIL), a genetic disease affecting the small arteries of the brain (see Chapter 9).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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