Androgen receptor function and prostate disease

The human prostate is a major site of disease, especially in elderly men. An increasing number is affected by prostate cancer and/orbenign prostate hyperplasia (BPH). Established risk factors are the presence of androgens and age (Cook and Watson 1968). In addition, genetic factors and environmental influences such as high saturated fat, low fruit/vegetable diet and decreased sunlight exposure (vitamin D production) and life style also influence the risk for prostate disease (Stanford et al. 1999). In benign prostate hyperplasia, the presence of the androgen DHT that stimulates prostate growth through androgen receptor activation seems to be critical and reduction of DHT levels by inhibition of 5a-reductase is a successful therapy (Bartsch et al. 2000). In addition, alterations of the AR signaling, function and structure are associated with the progression of prostate cancer from a hormone-sensitive to a therapy-refractory state.

Using Exercise To Get Rid Of Man Boobs

Using Exercise To Get Rid Of Man Boobs

In this guide, youll learn just what kinds of exercises you can use to get rid of man boobs forever. It includes two different types of exercises those designed to burn body fat, helping you lose excess weight all over your body and targeted chest exercises which will shrink your man boobs until you have a masculine, sexy chest.

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