Androgen receptor function and prostate disease

The human prostate is a major site of disease, especially in elderly men. An increasing number is affected by prostate cancer and/orbenign prostate hyperplasia (BPH). Established risk factors are the presence of androgens and age (Cook and Watson 1968). In addition, genetic factors and environmental influences such as high saturated fat, low fruit/vegetable diet and decreased sunlight exposure (vitamin D production) and life style also influence the risk for prostate disease (Stanford et al. 1999). In benign prostate hyperplasia, the presence of the androgen DHT that stimulates prostate growth through androgen receptor activation seems to be critical and reduction of DHT levels by inhibition of 5a-reductase is a successful therapy (Bartsch et al. 2000). In addition, alterations of the AR signaling, function and structure are associated with the progression of prostate cancer from a hormone-sensitive to a therapy-refractory state.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

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