Effects of testosterone on cardiomyocytes

In agreement with the association of testosterone and male sex with higher left ventricular mass as well as with the stimulating effect of exogenous testosterone on heart weight and contractility, testosterone was found to induce proliferation of isolated cardiomyocytes. This is in contrast to the antiproliferative effect of estrogens, which therefore suggests a direct effect of testosterone. This was also shown directly (Marsh et al. 1998). By contrast, the similar effect of testosterone and estradiol on the expression of the V1 myosin heavy chain isoenzyme may point to the importance of estradiol and the estrogen receptor for mediating this effect, although this was not shown directly (Lengsfeld etal. 1988; Morano etal. 1990).

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

Get My Free Ebook


Post a comment