Effects of testosterone on platelet function

Aggregation of platelets is a prerequisite for thrombus formation and hence a critical step in acute coronary events (Ruggeri 2002). Administration of testosterone cypionate to eugonadal men led to enhanced ex vivo platelet aggregation in response to the thromboxane analogue I-BOP but not in response to thrombin (Ajayi et al. 1995). Testosterone increases the expression of the androgen receptor in a megakaryocyte cell line, as well as in platelets (Matsuda et al. 1993; 1994). Flutamide inhibited the stimulatory effect of testosterone on thromboxane receptor expression (Matsuda etal. 1993; 1994) suggesting that the effect is mediated via the androgen receptor.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

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