The determination of LH and FSH plays a key role in establishing the diagnosis of hypogonadotropic (i.e. secondary) or hypergonadotropic (i.e. primary) hypo-gonadism. However, during surveillance of testosterone therapy they are of less importance. Negative feedback regulation between hypothalamus, pituitary and testes causes negative correlation between serum testosterone and LH, as well as to some extent to FSH levels in normal men.

In cases with primary hypogonadism (e.g. intact hypothalamic and pituitary function) FSH and in particular LH increase with decreasing testosterone levels and may normalize under testosterone treatment. This is especially the case in patients with acquired anorchia (e.g. due to accidents or iatrogenic castration). However, in the most frequent form of primary hypogonadism, i.e. in patients with Klinefelter syndrome, LH and FSH often do not show significant suppression during testosterone substitution. Moreover, oral or transdermal testosterone may have only little effect on gonadotropins. Therefore LH is not the best indicator of sufficient testosterone replacement therapy.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

Get My Free Ebook

Post a comment