One small double-blind, placebo-controlled cross-over study examined the effects of testosterone on short-term growth in boys with short stature on hemodialysis (Kassmann et al. 1992). After an 8-week run-in, eight boys (mean 3.9 SD below mean height for age) on regular hemodialysis were randomised to start on one of two four-week treatment periods separated by a six-week wash-out period before crossing over to the other treatment. Treatment consisted of 2 g/m2/day of a transdermal gel corresponding to a topical daily dose of 50 mg/m2 testosterone or placebo. Although a significant increase in short-term growth velocity (using knemometry) was reported overall, gain of final height was not reported and cannot be predicted from growth velocity. Furthermore, the small sample size and unbalanced randomisation were limitations. Further larger and longer studies would be needed before even low-dose androgen therapy could be considered effective or safe.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

Get My Free Ebook

Post a comment