HM Behre C Wang DJ Handelsman and E Nieschlag

Contents

14.1

Historical development of testosterone therapy

14.2

General considerations

14.3

Pharmacology of testosterone preparations

14.3.1

Oral administration

14.3.1.1

Unmodified testosterone

14.3.1.2

17a-methyltestosterone

14.3.1.3

Fluoxymesterone

14.3.1.4

Mesterolone

14.3.1.5

Testosterone undecanoate

14.3.2

Sublingual application

14.3.3

Buccal application

14.3.4

Nasal application

14.3.5

Rectal application

14.3.6

Intramuscular application

14.3.6.1

Testosterone propionate

14.3.6.2

Testosterone enanthate

14.3.6.3

Testosterone cypionate and testosterone cyclohexanecarboxylate

14.3.6.4

Testosterone ester combinations

14.3.6.5

Testosterone buciclate

14.3.6.6

Testosterone undecanoate

14.3.6.7

Testosterone decanoate

14.3.6.8

Testosterone microspheres

14.3.7

Subdermal application

14.3.7.1

Testosterone pellets

14.3.7.2

Testosterone microcapsules

14.3.8

Transdermal application

14.4

Key messages

14.5

References

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