Men exhibit a higher mass of red blood cells than women, which had already been demonstrated by spectrophotometry in 900 subjects almost 100 years ago (Williamson 1916). This fact cannot totally be accounted for by menstrual blood loss occuring in women and has been shown to be caused by higher androgen levels present in men (Vahlquist 1950). The marked influence of androgens on erythropoiesis was a major endocrinological research topic during the 1970s (for review: Shahidi 1973). Although the prime time of androgen therapy for anemia passedwith the introduction of recombinant erythropoietin (rhEPO) in 1987, androgens continue to be widely used for testosterone substitution therapy in hypogonadal men who often present with markedly lowered hemoglobin and erythrocyte concentrations. Nevertheless, the general issue of androgens in relation to erythropoiesis seems to be experiencing a current revival. The effects of androgens on erythro-poiesis are exerted via several pathways which will be discussed. Safety aspects concerning increased red blood cell mass in terms of a putatively affected risk for ischemic vascular disease will also be considered.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

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