Mesterolone can be considered a derivative ofthe 5a-reduced testosterone metabolite 5a-dihydrotestosterone (DHT) which is protected from rapid metabolism in the liver by a methyl group in position 1 (Gerhards et al. 1966) and thus becomes orally active. It is free of liver toxicity. Unlike testosterone, mesterolone cannot be metabolized to estrogens (Breuer and Gutgemann 1966) and at a molecular level acts like DHT. Because of its limited effectiveness in suppressing pituitary gonadotropin secretion (Aakvaag and Stromme 1974; Gordon et al. 1975) it can only be considered an incomplete androgen. Altogether, mesterolone is not suited for the substitution of hypogonadism. Nevertheless, in 2001 it still represented 12% of all androgen sales in Germany.

Hair Loss Prevention

Hair Loss Prevention

The best start to preventing hair loss is understanding the basics of hair what it is, how it grows, what system malfunctions can cause it to stop growing. And this ebook will cover the bases for you. Note that the contents here are not presented from a medical practitioner, and that any and all dietary and medical planning should be made under the guidance of your own medical and health practitioners. This content only presents overviews of hair loss prevention research for educational purposes and does not replace medical advice from a professional physician.

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