WSchanzer

Contents

24.1

Introduction

24.2

Frequency of steroid hormone misuse

24.2.1

Androgen misuse in controlled competition sports

24.2.2

Androgen misuse in non-controlled sports

24.3

Prohormones of androgens

24.4

Contamination of nutritional supplements with prohormones

24.5

Detection of misuse of anabolic androgenic steroid hormones

24.5.1

Organization of doping tests

24.5.2

Detection and identification of misused anabolic androgenic steroids

24.5.2.1

Metabolism

24.5.2.2

Pharmacokinetics

24.5.2.3

Sample preparation

24.5.2.4

Derivatization

24.5.3

Detection of synthetic anabolic androgenic steroids

24.5.4

Detection of endogenous anabolic androgenic steroids

24.5.4.1

Indirect detection methods

24.5.4.2

Direct detection method: gas chromatography - combustion - isotope

ratio mass spectrometry (GC-C-IRMS)

24.6

Key messages

24.7

References

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