It is clear that pervasive deficits in emotional status occur in the wake of a TBI. Problems have emerged in the specification of this deficit due to issues associated with the nature of the relationship between the injury, the substrate upon which the injury acts, and the effects of the injury on the individual's life and circumstance in the wake of the blow. It is clear that approximately 20-30% of individuals will have a diagnosable affective disorder following the injury and that this level of deficit will persist for a number of years. The literature on the relationship of the side and site of the blow has been less than conclusive and it now seems most likely that there is no direct relationship between the site or side of the injury and the subsequent affective state.

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